Berlin

CRS BERLIN

CRS Clinical Research Services Berlin GmbH
Sellerstrasse 31, Gebäude P300
13353 Berlin
Germany
+49 30 859 949 – 0

CRS´ Highly Specialized Clinical Pharmacology Unit (CPU)

CRS Berlin is housed in the top floor of an appealing building located in the heart of Berlin. Owing to the complex floor plan and an intelligent access control system in-house and outpatient clinical trial activities can be spatially separated, allowing the simultaneous conduct of several studies without interference.

20 INTENSIVE MONITORING BEDS AND SIX CONVENIENT DOUBLE ROOMS ARE AVAILABLE

Accordingly, the CRS Berlin unit has 20 intensive monitoring beds available, each equipped with a computerized ECG device, systems for continuous blood oxygen saturation (SpO2) measurement and vital signs monitoring, plus eight convenient rooms, each with two beds. Furthermore, CRS Berlin comprises several examination rooms, a gynecological unit with two examination chairs, state-of-the-art ultrasound equipment, as well as various laboratories for cardiometabolic assessments and immediate blood and urine processing.

CRS Berlin and its Outstanding Expertise

A major scope of the CRS Berlin unit is the conduct of early phase clinical trials in the area of women’s health, including postmenopausal women. This especially covers first-in-human (FiH) and long-term outpatient studies with challenging pharmacokinetic (PK) / pharmacodynamic (PD) designs including a broad spectrum of medicine administration routes (oral, dermal, subcutaneous, intravenous, intravaginal, intrauterine). It also covers early phase clinical trials with special populations such as women with endometriosis or polycystic ovary syndrome (PCOS). A plurality of established as well as experimental gynecological methods are applied by board certified gynecologist at our site, e.g., standard gynecological examinations, transvaginal ultrasound, vaginal cytology, endometrial biopsy, Insler and Hoogland scores – these are just some examples illustrating the techniques in command of CRS Berlin.

Outpatient studies with women of childbearing potential can be conducted either cycle-dependent or with a synchronizing cycle intervention preceding the treatment phase, which is leading to more grouped treatment schedules.

WE REALIZE CLINICAL TRIALS IN ALL COMMON TRIAL DESIGNS

Moreover, the CRS Berlin unit has accumulated significant expertise regarding the implementation of clinical trials in all common trial designs, e.g., human pharmacological trials with contrast agents and specialized therapeutics and trials in cardiometabolic indications such as obesity, insulin resistance, diabetes, and cardiovascular disease.

Thus, CRS Berlin can realize a wide range of study types supported by a database with a large diversity of volunteer populations.

The team of the CRS Berlin unit is highly competent in planning and conducting clinical research in vulnerable people and complex conditions. Key terms for what is meant are:

  • Healthy volunteers
  • Women‘s health
  • Men‘s health
  • Elderly subjects
  • Early clinical research phase I and II – first-in-human (FiH)
  • Long-term outpatient studies
  • Trials with challenging pharmacokinetic (PK) / pharmacodynamic (PD) designs
  • Trials employing different medicine administration routes (oral, dermal, subcutaneous, intravenous, intravaginal, intrauterine)
  • Trials applying established and experimental gynecological methods (e.g., standard gynecological examinations, transvaginal ultrasound, vaginal cytology, endometrial biopsy, Insler and Hoogland scores)
  • Human pharmacological trials with contrast agents  and specialized therapeutics
  • Trials in cardiometabolic indications such as obesity, insulin resistance, diabetes, and cardiovascular disease.

The Medical Director of CRS Berlin, Dr Sybille Baumann, also CRS Board Member, is certified in clinical pharmacology and anesthesiology. She is an experienced clinician and clinical pharmacologist with more than 25 years of extensive experience in over 250 clinical trials as principal or co-investigator. A highly dedicated team of qualified clinic employees contributes to the successful conduct of trials.

CRS Berlin is located in the heart of Berlin, within walking distance of the “Campus Charité Mitte”, the “Virchow Klinikum”, and the central train station – easily accessible by trial participants and customers from Berlin and elsewhere. Berlin, the largest city in Germany with over 3.5 million inhabitants, is a hotspot for clinical research and life sciences.

The CRS Berlin unit has a separate entrance, an automatic access control system, and an independent technical infrastructure. All this guarantees for a strict segregation from the neighborhood – a precondition for investigating confidence in our exclusive work and sensitive data.

Infrastructure & Location

CRS-Berlin is housed in the top floor of an appealing building on the brink of the Bayer site in Berlin. A separate entrance, an automatic access control system and an independent technical infrastructure guarantees for a strict segregation from the circumjacent Bayer facilities.

20 intensive care daybeds and 8 convenient double rooms are avaliable.

Owing to the complex floor plan and an intelligent access control system in-house and outpatient clinical trial activities can be spatially separated allowing the simultaneous conduct of several studies without interference. 20 intensive care beds, each equipped with an ECG, SpO2 and vital signs monitoring system, a computerized ECG device and an EDC system, as well as 6 convenient double rooms are available for this purpose. Furthermore, CRS-Berlin comprises several examination rooms, a gynecological unit with two examination chairs as well as various laboratories for immediate blood and urine processing.

Network of Expertise

  • Healthy Volunteers
  • Women‘s Health
  • Men‘s Health
  • Early Research Unit in Berlin

Owing to the specialised layout of CRS-Berlin, in-house and outpatient clinical trial activities can be spatially separated allowing several studies to be run simultaneously without cross-interference. This CPU contains 20 intensive care beds, each equipped with an ECG, SpO2 and vital signs monitoring system, a computerised ECG device, as well as 8 convenient double rooms (i.e. 16 beds). CRS-Berlin also comprises several examination rooms, a gynaecological unit with two examination chairs, state-of-the-art ultrasound equipment and various laboratories for immediate blood and urine processing. On-site gynaecological examinations, including Isler- and Hoogland scoring, endometrial biopsies and transvaginal ultrasounds (TVUS), are just a few selected examples illustrating the benefits of working with CRS-Berlin.

CRS-Berlin has gained outstanding expertise in women’s healthcare.

Conducting studies involving women with childbearing potential and post-menopausal women, this specifically covers FIM and long-term outpatient studies with challenging PK/PD designs including a wide spectrum of administration routes (oral, dermal, subcutaneous, intravenous, intravaginal and intrauterine) and early clinical trials with special populations such as tubal ligated women. CRS-Berlin also has significant expertise in implementing human pharmacological trials with cardiovascular drugs, contrast agents and specialised therapeutics in all common designs. CRS-Berlin can therefore undertake a wide range of study types supported by a database containing diverse volunteer populations.

Dr Sybille Baumann, a board member certified in clinical pharmacology and anaesthesiology, is the medical director of CRS-Berlin. Dr. Baumann is an experienced Clinician and Clinical Pharmacologist with more than 25 years’ extensive experience in over 350 clinical drug studies as co- and principal investigator. A highly dedicated team of 30 qualified clinic employees and 15 Freelancers contributes to the successful conduct of trials.

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REACHING OUT IS EASY AND FAST – LET’S TALK

Dr. Sybille Baumann

Medical Director
CRS Berlin


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Dr. Volker Menschik

Chief Business Officer (CBO)
located at CRS Berlin


LET’S TALK BUSINESS

CRO Leadership Awards 2019

CRS is proud to be recognised again by pharma companies worldwide as a leading CRO with regard to: capabilities, compatibility, quality and reliability.

European Biotechnology Guide

Find CRS’s company profile in the European Biotechnology Science Industry Guide, volume 9 2019.

EcoVadis – CSR Rating

Based on the CSR rating by EcoVadis in July 2018 CRS has been granted Silver Recognition Level.