renal impairment Archives - CRS. Experts. Early Phase.

Pharmacokinetics, pharmacodynamics and safety of empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, in subjects with renal impairment.

Science 21. November 2022

First published in Diabetes, Obesity and Metabolism on 2014 Mar.Diabetes Obes Metab. 2014 Mar;16(3):215-22. doi: 10.1111/dom.12182. Epub 2013 Aug 19....

Read Article

Clinical overview of linagliptin, a dipeptidyl peptidase-4 inhibitor, in patients with Type 2 diabetes mellitus.

Science 21. November 2022

ShareTwitter FacebookXingLinkedin

First published in Expert Review of Endocrinology & Metabolism on 2013 Jan.Expert Rev Endocrinol Metab. 2013 Jan;8(1):21-35. doi: 10.1586/eem.12.69. Authors:...

Read Article

Pharmacokinetics of Teneligliptin in Subjects With Renal Impairment.

Science 21. November 2022

ShareTwitter FacebookXingLinkedin

First published in Clinical Pharmacology in Drug Development on 2013 Jul. Clin Pharmacol Drug Dev. 2013 Jul;2(3):246-54. doi: 10.1002/cpharmacodynamicsd.29. Epub...

Read Article

Impact of impaired renal function on the pharmacokinetics of the antiepileptic drug lacosamide.

Science 21. November 2022

ShareTwitter FacebookXingLinkedin

First published in Clinical Pharmacokinetics on 2013 Oct.Clin Pharmacokinet. 2013 Oct;52(10):897-906. doi: 10.1007/s40262-013-0080-7. Authors: Cawello W, Fuhr U, Hering U,...

Read Article

Effects of renal impairment on the pharmacokinetics, pharmacodynamics and safety of rivaroxaban, an oral, direct Factor Xa inhibitor.

Science 10. November 2022

ShareTwitter FacebookXingLinkedin

First published in British Journal of Clinical Pharmacology on 2010 Nov.Br J Clin Pharmacol. 2010 Nov;70(5):703-12. doi: 10.1111/j.1365-2125.2010.03753.x. Authors: Kubitza...

Read Article

Single-dose pharmacokinetics, safety, and tolerability of albinterferon alfa-2b in subjects with end-stage renal disease on hemodialysis compared to those in matched healthy volunteers.

Science 10. November 2022

ShareTwitter FacebookXingLinkedin

First published in Antimicrobal Agents and Chemotherapy on 2011 Feb.Antimicrob Agents Chemother. 2011 Feb;55(2):473-7. doi: 10.1128/AAC.00626-10. Authors: Serra DB, Sun...

Read Article

Effect of renal impairment on the pharmacokinetics of the dipeptidyl peptidase-4 inhibitor linagliptin(*).

Science 10. November 2022

ShareTwitter FacebookXingLinkedin

First published in Diabetes, Obesity and Metabolism on 2011 Oct.Diabetes Obes Metab. 2011 Oct;13(10):939-46. doi: 10.1111/j.1463-1326.2011.01458.x. Authors: Graefe-Mody U, Friedrich...

Read Article

Tolerability, pharmacokinetics, and bioequivalence of the tablet and syrup formulations of lacosamide in plasma, saliva, and urine: saliva as a surrogate of pharmacokinetics in the central compartment.

Science 10. November 2022

ShareTwitter FacebookXingLinkedin

First published in Epilepsia on 2013 Jan.Epilepsia. 2013 Jan;54(1):81-8. doi: 10.1111/j.1528-1167.2012.03725.x. Authors: Cawello W, Bökens H, Nickel B, Andreas JO,...

Read Article

Pharmacokinetics of teduglutide in subjects with renal impairment.

Science 10. November 2022

ShareTwitter FacebookXingLinkedin

First published in European Journal of Clinical Pharmacology on 2013 May.Eur J Clin Pharmacol. 2013 May;69(5):1149-55. doi: 10.1007/s00228-012-1455-7. Authors: Nave...

Read Article

Pharmacokinetics of serelaxin in patients with severe renal impairment or end-stage renal disease requiring hemodialysis: A single-dose, open-label, parallel-group study.

Science 10. November 2022

ShareTwitter FacebookXingLinkedin

First published in The Journal of Clinical Pharmacology on 2016 Apr.J Clin Pharmacol. 2016 Apr;56(4):474-83. doi: 10.1002/jcph.607. Authors: Dahlke M,...

Read Article