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A single-blinded, single-centre, controlled study in healthy adult smokers to identify the effects of a reduced toxicant prototype cigarette on biomarkers of exposure and of biological effect versus commercial cigarettes.

Science 11. November 2022
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First published in BMC Public Health on 2013 Jul.BMC Public Health. 2013 Jul 29;13:690. doi: 10.1186/1471-2458-13-690 Authors: Shepperd CJ, Newland...
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Detection of obstructive sleep apnoea by an electronic nose.

Science 10. November 2022
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First published in European Respiratory Journal on 2013 Jul.Eur Respir J. 2013 Jul;42(1):145-55. doi: 10.1183/09031936.00091712. Authors: Greulich T, Hattesohl A,...
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Natural innate cytokine response to immunomodulators and adjuvants in human precision-cut lung slices.

Science 10. November 2022
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First published in Toxicology and Applied Pharmacology on 2010 Aug.Toxicol Appl Pharmacol. 2010 Aug 1;246(3):107-15. doi: 10.1016/j.taap.2010.04.010. Authors: S.Switalla, L.Lauenstein,...
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Coagulation status in coronary artery disease patients with type II diabetes mellitus compared with non-diabetic coronary artery disease patients using the PFA-100® and ROTEM®.

Science 10. November 2022
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First published in Platelets on 2010Platelets. 2010;21(8):616-22. doi: 10.3109/09537104.2010.504868. Authors: M. Feuring, M. Wehling, H. Burkhardt, A. Schultz Abstract Previous...
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NGF induces non-inflammatory localized and lasting mechanical and thermal hypersensitivity in human skin.

Science 10. November 2022
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First published in Pain on 2010 Mar.Pain. 2010 Mar;148(3):407-13. doi: 10.1016/j.pain.2009.11.022.  Authors: Rukwied R, Mayer A, Kluschina O, Obreja O,...
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Segmental allergen challenge alters multimeric structure and function of surfactant protein D in humans.

Science 10. November 2022
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First published in American Journal of Respiratory and Critical Care Medicine on 2011 Apr.Am J Respir Crit Care Med. 2011...
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Anti-allergic drug testing in an environmental challenge chamber is suitable both in and out of the relevant pollen season.

Science 10. November 2022
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First published in Annals of Allergy, Asthma & Immunology on 2011 Apr.Ann Allergy Asthma Immunol. 2011 Apr;106(4):336-41. doi: 10.1016/j.anai.2010.12.018. Authors:...
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Lepirudin dose-dependently increases thrombelastography parameters at therapeutic plasma concentrations as measured with ROTEM® – a pilot study.

Science 10. November 2022
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First published in Int. Journal of Clinical Pharmacology and Therapeutics on 2011 Oct.Int J Clin Pharmacol Ther. 2011 Oct;49(10):626-8 Authors:...
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Dalteparin dose-dependently increases ROTEM(®) thrombelastography parameters only at supratherapeutic anti-factor Xa levels: an in vitro study.

Science 10. November 2022
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First published in Clinical and Experimental Pharmacology and Physiology on 2011 Nov.Clin Exp Pharmacol Physiol. 2011 Nov;38(11):783-6. doi: 10.1111/j.1440-1681.2011.05593.x. Authors:...
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Low-dose endotoxin inhalation in healthy volunteers–a challenge model for early clinical drug development.

Science 10. November 2022
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First published in BMC Pulmonary Medicine on 2013 Mar.BMC Pulm Med. 2013 Mar 28;13:19. doi: 10.1186/1471-2466-13-19 Authors: Janssen O, Schaumann...
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