Insulin Archives - CRS. Experts. Early Phase.

Standardized modulation of the injection site allows for insulin dose reduction without deterioration of metabolic control.

Science 21. November 2022

First published in Current Medical Research and Opinion on 2014 Oct.Curr Med Res Opin. 2014 Oct;30(10):2001-8. doi: 10.1185/03007995.2014.933098. Epub 2014...

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The Barmer study: impact of standardized warming of the injection site to enhance insulin absorption and reduce prandial insulin requirements and hypoglycemia in obese patients with diabetes mellitus.

Science 21. November 2022

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First published in Current Medical Research and Opinion on 2014 May. Curr Med Res Opin. 2014 May;30(5):753-60. doi: 10.1185/03007995.2014.880049. Epub...

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Effects of insulin glargine versus metformin on glycemic variability, microvascular and beta-cell function in early type 2 diabetes.

Science 21. November 2022

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First published in Acta Diabetologica in 2013 Aug.Acta Diabetol. 2013 Aug;50(4):587-95. doi: 10.1007/s00592-012-0451-9. Epub 2013 Feb 21. Authors: Pistrosch F,...

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Adding insulin glargine vs. NPH insulin to metformin results in a more efficient postprandial beta-cell protection in individuals with type 2 diabetes.

Science 10. November 2022

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First published in Diabetes, Obesity and Metabolism on 2010 May.Diabetes Obes Metab. 2010 May;12(5):437-41. doi: 10.1111/j.1463-1326.2010.01209.x Authors: Forst T, Larbig...

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Evaluation of dexterity in insulin-treated patients with type 1 and type 2 diabetes mellitus.

Science 10. November 2022

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First published in Journal of Diabetes Science and Technology on 2011 Jan.J Diabetes Sci Technol. 2011 Jan 1;5(1):158-65 Authors: Pfützner...

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Non-glycemic effects of insulin therapy: a comparison between insulin aspart and regular human insulin during two consecutive meals in patients with type 2 diabetes.

Science 10. November 2022

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First published in European Journal of Endocrinology on 2011 Aug.Eur J Endocrinol. 2011 Aug;165(2):269-74. doi: 10.1530/EJE-11-0061. Authors: Sourij H, Schmoelzer...

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Comparison of the Effects of Pioglitazone versus Placebo when Given in Addition to Standard Insulin Treatment in Patients with Type 2 Diabetes Mellitus Requiring Hemodialysis: Results from the PIOren Study.

Science 9. November 2022

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First published in Nephron Extra on 2012 Jan.Nephron Extra. 2012 Jan;2(1):104-14. doi: 10.1159/000337334. Epub 2012 May 4 Authors: Galle J,...

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In type 2 diabetes patients, insulin glargine is associated with lower postprandial release of intact proinsulin compared with sulfonylurea treatment.

Science 9. November 2022

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First published in Diabetes Technology Society on 2012 May.J Diabetes Sci Technol. 2012 May 1;6(3):634-40 Authors: Pscherer S, Larbig M,...

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Adding once-daily lixisenatide for type 2 diabetes inadequately controlled with newly initiated and continuously titrated basal insulin glargine: a 24-week, randomized, placebo-controlled study (GetGoal-Duo 1).

Science 9. November 2022

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Diabetes Care. 2013 Sep;36(9):2497-503. doi: 10.2337/dc12-2462. Authors: Riddle MC, Forst T, Aronson R, Sauque-Reyna L, Souhami E, Silvestre L, Ping...

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Contrasting Effects of Lixisenatide and Liraglutide on Postprandial Glycemic Control, Gastric Emptying, and Safety Parameters in Patients With Type 2 Diabetes on Optimized Insulin.

Science 28. September 2022

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This open-label, nonrandomized, single-dose, phase 1 study evaluated the pharmacokinetics and safety of murepavadin, a novel peptide antibiotic for the treatment of serious Pseudomonas aeruginosa infections.

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