Pharmacokinetic interactions between simvastatin and setipiprant, a CRTH2 antagonist.
First published in European Journal of Clinical Pharmacology on 2015 Jan.Eur J Clin Pharmacol. 2015 Jan;71(1):15-23. doi: 10.1007/s00228-014-1767-x. Epub 2014 Oct 18. Authors: Gehin M, Sidharta PN, Gnerre C, Treiber A, Halabi A, Dingemanse J. Read more Download full article as Pdf file: Pdf File … read more
Effect of faldaprevir on raltegravir pharmacokinetics in healthy volunteers.
First published in The Journal of Clinical Pharmacology on 2015 Apr.J Clin Pharmacol. 2015 Apr;55(4):384-91. doi: 10.1002/jcph.418. Epub 2014 Dec 8. Authors: Joseph D, Rose P, Strelkowa N, Schultz A, Garcia J, Elgadi M, Huang F Read more Download full article as Pdf file: Pdf File … read more
Inter- and intrasubject variability of the inflammatory response to segmental endotoxin challenge in healthy volunteers.
First published in Pulmonary Pharmacology & Therapeutics on 2015 Dec.Pulm Pharmacol Ther. 2015 Dec;35:50-9. doi: 10.1016/j.pupt.2015.10.011. Epub 2015 Nov 10. Authors: Holz O, Tan L, Schaumann F, Müller M, Scholl D, Hidi R, McLeod A, Krug N, Hohlfeld JM Read more Download full article as Pdf file: Pdf File… read more
Evaluation of the effect of food and age on the pharmacokinetics of oral netupitant and palonosetron in healthy subjects: A randomized, open-label, crossover phase 1 study.
First published in Clinical Pharmacology in Drug Development on 2015 Sep.Clin Pharmacol Drug Dev. 2015 Sep;4(5):377-86. doi: 10.1002/cpharmacodynamicsd.192. Epub 2015 May 29. Authors: Calcagnile S, Lanzarotti C, Gutacker M, Jakob-Rodamer V, Peter Kammerer K, Timmer W Read more Download full article as Pdf file: Pdf File … read more
Pharmacokinetics and adhesion of a transdermal patch containing ethinyl estradiol and gestodene under conditions of heat, humidity, and exercise: A single-center, open-label, randomized, crossover study.
First published in Clinical Pharmacology in Drug Development on 2015 Jul.Clin Pharmacol Drug Dev. 2015 Jul;4(4):245-55. doi: 10.1002/cpharmacodynamicsd.185. Epub 2015 May 8. Authors: Zurth C, Schuett B, Casjens M, Ludwig M, Waellnitz K Read more Download full article as Pdf file: Pdf File read more
Safety and tolerability of a novel inhaled GATA3 mRNA targeting DNAzyme in patients with TH2-driven asthma.
First published in The Journal of Allergy and Clinical Immunology on 2015 Sep.J Allergy Clin Immunol. 2015 Sep;136(3):797-800. doi: 10.1016/j.jaci.2015.02.018. Epub 2015 Apr 2. Authors: Homburg U, Renz H, Timmer W, Hohlfeld JM, Seitz F, Lüer K, Mayer A, Wacker A, Schmidt O, Kuhlmann J, Turowska A, Roller J, Kutz K, Schlüter G, Krug N,… read more
Safety and tolerability of a novel inhaled GATA3 mRNA targeting DNAzyme in patients with TH2-driven asthma.
First published in The Journal of Allergy and Clinical Immunology on 2015 Sep.J Allergy Clin Immunol. 2015 Sep;136(3):797-800. doi: 10.1016/j.jaci.2015.02.018. Epub 2015 Apr 2. Authors: Homburg U, Renz H, Timmer W, Hohlfeld JM, Seitz F, Lüer K, Mayer A, Wacker A, Schmidt O, Kuhlmann J, Turowska A, Roller J, Kutz K, Schlüter G, Krug N,… read more
Single therapeutic and supratherapeutic doses of corifollitropin alfa, a sustained follicle stimulant, do not prolong the QTcF-interval in healthy postmenopausal volunteers.
First published in Int. Journal of Clinical Pharmacology and Therapeutics on 2015 Sep.Int J Clin Pharmacol Ther. 2015 Sep;53(9):772-82. doi: 10.5414/CP202363. Authors: de Kam PJ, van Kuijk JH, Zandvliet AS, Thomsen T Read more Download full article as Pdf file: Pdf File read more
Noninvasive quantification of airway inflammation following segmental allergen challenge with functional MR imaging: a proof of concept study.
First published in Radioloy on 2015 Jan.Radiology. 2015 Jan;274(1):267-75. doi: 10.1148/radiol.14132607. Epub 2014 Sep 8. Authors: Renne J, Hinrichs J, Schönfeld C, Gutberlet M, Winkler C, Faulenbach C, Jakob P, Schaumann F, Krug N, Wacker F, Hohlfeld JM, Vogel-Claussen J Read more Download full article as Pdf file: Pdf… read more
Desmethyl bosentan displays a similar in vitro interaction profile as bosentan.
First published in Pulmonary Pharmacology & Therapeutics on 2015 Feb.Pulm Pharmacol Ther. 2015 Feb;30:80-6. doi: 10.1016/j.pupt.2014.12.001. Epub 2014 Dec 19 Authors: Weiss J, Baumann S, Theile D, Haefeli WE. Read more Download full article as Pdf file: Pdf File read more
Pharmacokinetic interaction between the CYP3A4 inhibitor ketoconazole and the hormone drospirenone in combination with ethinylestradiol or estradiol.
First published in British Journal of Clinical Pharmacology on 2015 Dec.Br J Clin Pharmacol. 2015 Dec;80(6):1399-410. doi: 10.1111/bcp.12745. Epub 2015 Oct 28. Authors: Wiesinger H, Berse M, Klein S, Gschwend S, Höchel J, Zollmann FS, Schütt B Read more Download full article as Pdf file: Pdf File … read more
Standardized modulation of the injection site allows for insulin dose reduction without deterioration of metabolic control.
First published in Current Medical Research and Opinion on 2014 Oct.Curr Med Res Opin. 2014 Oct;30(10):2001-8. doi: 10.1185/03007995.2014.933098. Epub 2014 Jul 4. Authors: Pfützner A, Dissel S, Forkel C, Grenningloh M, Bitton G, Nagar R, Forst T Read more Download full article as Pdf file: Pdf File … read more
CRO Leadership Awards 2019
CRS is proud to be recognised again by pharma companies worldwide as a leading CRO with regard to: capabilities, compatibility, quality and reliability.
European Biotechnology Guide
Find CRS’s company profile in the European Biotechnology Science Industry Guide, volume 9 2019.
EcoVadis – CSR Rating
Based on the CSR rating by EcoVadis in 2022 CRS has been granted Silver Recognition Level.