Effect of Diet on Serum Creatinine in Healthy Subjects During a Phase I Study.


First published in Journal of Clinical Medicine Research on 2016 Nov.
J Clin Med Res. 2016 Nov;8(11):836-839. Epub 2016 Sep 29

Authors: Pimenta E, Jensen M, Jung D, Schaumann F, Boxnick S, Truebel H


Creatinine is widely used as an indirect marker of renal function. However, interfering factors such as diet, exercise and problems with the assay can generate false results and misinterpretation of real kidney function. In this article, we report the dietary effects on serum creatinine during a phase I single dose escalation study and discuss the reasons why serum creatinine should be measured under fasting conditions.

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