Slide 1WE ARE EARLY PHASESlide 2TRIAL EXPERTISESlide 3THERAPEUTIC EXPERTISE We are EARLY Phase We do one thing only, and we do it reliably in all shapes and colours – even yours. FIND OUT WHO WE ARE Trial Expertise We deliver reliable research on everything first-in-human. And we do it in every relevant field and in our own clinical facilities. LEARN ABOUT OUR METHODOLOGIES Therapeutic EXPERTISE Our specialised units in 4 locations handle indications that range from cardiovascular to respiratory. SEE OUR EXPERTISE BY INDICATION News Company News Very soon – we are moving to Berlin’s TechnoCampus Company News CRS Clinical Research Services Berlin zieht um. Scientific News First patient has been enrolled in a Phase 1a/b study with Atrogi’s drug candidate ATR-258. Scientific News New Whitepaper: New strategies to improve clinical outcomes for diabetic kidney disease Company News Herzinsuffizienz und Diabetes Company News 100 Jahre Insulin More News Publications British Journal of Clinical Pharmacology Bioequivalence of macitentan and tadalafil given as fixed-dose combination or single-component tablets in healthy subjects. British Journal of Clinical Pharmacology Midazolam microdosing applied in early clinical development for drug-drug interaction assessment. British Journal of Clinical Pharmacology The effects of vilaprisan on the pharmacodynamics and pharmacokinetics of a combined oral contraceptive – A randomized controlled trial. British Journal of Clinical Pharmacology Safety, pharmacokinetics and pharmacodynamics of BI 705564, a highly selective, covalent inhibitor of Bruton’s tyrosine kinase, in Phase I clinical trials in healthy volunteers. Diabetes Metabolism Research and Reviews A practical approach to the clinical challenges in initiation of basal insulin therapy in people with type 2 diabetes. Klinische Monatsblätter für Augenheilkunde Diabetic Macular Edema in Diabetological Practices. More Publications Studies in cooperation with: REACHING OUT IS EASY AND FAST – LET’S TALK Prof. Dr. Thomas Forst Chairman of the Executive Boardlocated at CRS Mannheim LET’S TALK SCIENCE *protected email* +49 621 150 45 – 0 Dr. Marc Hetzel VP & Head of Business Developmentlocated at CRS Management LET’S TALK BUSINESS *protected email* +49 621 150 45 – 0 CRO Leadership Awards 2019 CRS is proud to be recognised again by pharma companies worldwide as a leading CRO with regard to: capabilities, compatibility, quality and reliability. European Biotechnology Guide Find CRS’s company profile in the European Biotechnology Science Industry Guide, volume 9 2019. EcoVadis – CSR Rating Based on the CSR rating by EcoVadis in 2022 CRS has been granted Silver Recognition Level.