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    Search for "effect"

    Displaying results 1 to 10 out of 11

      1981 – 1989 81%
      ... 1989 . Kirch W, Halabi A , Ohnhaus EE. Negative effects of famotidine on cardiac performance assessed by ... and nitrendipine. Comparison of their haemodynamic effects. 18th Annual Meeting of the American College of ... 1989 . Kirch W, Nokhodian A, Schacht A, Halabi A . Effects of anipamil on renal function in hypertensives. IV ... Nix N, Sourgens H, Thomsen T . A study to test the
      Size: 41 K - Created: 18-11-12 - Modified: 02-08-19 10:27
    Path: /Expertise/Published Expertise/1981 – 1989

      1990 – 1999 76%
      ... J, Popescu C, Hucke HP, Eckl KM, Roots I. No effect of liver impairment on the pharmacokinetics of ... A, Hucke HP, Kurowski M, Eckl KM. Voglibose has no effect on the pharmacokinetics of hydrochlorothiazide. Eur J ... T , Möller M , Violet I, Dubois F. The bradycardic effect of the sinuatrial modulator S16257. Eur Heart J 1997 ... Y, Möller M . Cholestyramine does not impair the
      Size: 61 K - Created: 18-11-12 - Modified: 02-08-19 10:27
    Path: /Expertise/Published Expertise/1990 – 1999

      Pharmacodynamic Expertise 76%
      Pharmacodynamic Expertise The identification of clinical effective drug candidates in the early clinical trial conduct is the key benefit of biomarkers. Due to changes in biomarker patterns it is possible to distinguish between effective and ineffective drug therapy, which enables “go/no-go” decisions for the clinical drug development ...
      Size: 34 K - Created: 18-11-12 - Modified: 02-08-19 10:27
    Path: /Expertise/Pharmacodynamic Expertise

      Locations 75%
      ... German "Bundesländer" (Federal States) represent ca. 35 million inhabitants. Accessibility to several million people is one of the basics for effective recruitment of patients, healthy volunteers or symptom bearing subjects, a prerequisite for the conduct of large scale, long-standing ...
      Size: 31 K - Created: 18-11-12 - Modified: 30-09-19 19:33
    Path: /Locations

      Info-Point 74%
      ... copyrigths on these materials - do not publish any material without prior agreement by CRS. Scientific Publications / White Papers Poster Effect of Multiple Oral Doses of NOMAC/E2 on QTcF Intervals  Press Releases Press release CRS receives CRO Leadership Awards 2019 Press release ...
      Size: 38 K - Created: 18-11-12 - Modified: 02-08-19 10:28
    Path: /Info-Point

      2010-2020 74%
      ... C, Casjens M , Loewen S, Zimmermann T, Rohde B. The effects of vilaprisan on the pharmacodynamics and ... Soergel M, Stepanova R, Sabattini G, Perez-Ruixo JJ. Effect of Macitentan on the Pharmacokinetics of the Breast ... S, Zimmermann T, Halabi A , Schultze-Mosgau MH. Effect of hepatic impairment on the pharmacokinetics of ... B, Höchel J, Schultze-Mosgau MH. CYP3A4-mediated
      Size: 71 K - Created: 09-11-15 - Modified: 08-07-20 10:17
    Path: /Expertise/Published Expertise/2010-2020

      2000 – 2009 72%
      ... P, Subar M, Abreu P, Thomsen T , Banke-Bochita J. Effects of steroidal and nonsteroidal aromatase inhibitors ... Schultz A , Losel R, Wehling M, Christ M, Feuring M. Effect of oral contraceptives and ovarian cycle on platelet ... PG, Bagchus W, Lass H, Thomsen T , Geurts TB. The effect of food composition on serum testosterone levels ... , Losel R, Wehling M. Monitoring Acetylsalicylic Acid
      Size: 53 K - Created: 09-11-15 - Modified: 02-08-19 10:27
    Path: /Expertise/Published Expertise/2000 – 2009

      CDM & STAT 69%
      ... relevant formats. As a result, CRS complies with project schedules while meeting the highest standards of quality in the most efficient, cost-effective manner. Biometrics The experienced, well-trained Biostatistical Department at CRS provides statistical analysis and programming adhering to ...
      Size: 31 K - Created: 18-11-12 - Modified: 02-08-19 10:27
    Path: /Services/CDM & STAT

      Trial Expertise 68%
      ... have been published since 1981. Drug-genotype interaction CRS conducts various trials in this field to support the increase of beneficial effects and to enhance the prevention of negative effects from drug therapy. Because genetic factors affect human responses to therapeutic drugs, CRS has access to a broad range of genotyped subjects ...
      Size: 34 K - Created: 18-11-12 - Modified: 02-08-19 10:27
    Path: /Expertise/Trial Expertise

      Special Populations 67%
      ... has experience of glucose clamp trials.  Male Fertile Subjects : CRS has carried out several fertility trials to measure the spermatogenesis effects of new compounds according to WHO criteria. Usually these kinds of trials require extended screening procedures to select healthy males who ...
      Size: 32 K - Created: 18-11-12 - Modified: 02-08-19 10:27
    Path: /Expertise/Special Populations

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