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|... volunteers is part of CRS’s standard routine. Genotyped Subjects: Over 3,000 healthy subjects are genotyped for the cytochrome P450 genes CYP2D6 (> 100 poor metabolizers), CYP2C9 (> 170 PM) and CYP2C19 (> 90 PM). Additional panels such as UGT1A1 characterisation are in preparation. ...|
|Size: 33 K - Created: 18-11-12 - Modified: 20-12-17 11:58
Path: /Expertise/Special Populations
|... P, Rembratt A, Schultz A, Timmer W, (2012) Pharmacokinetic and tolerability profile of pridopidine in healthy-volunteer poor and extensive CYP2D6 metabolizers, following single and multiple dosing. Eur J Drug Metab Pharmacokinet 2012, Sept 5 (Epub ahead of print) Härtter S, ...|
|Size: 65 K - Created: 09-11-15 - Modified: 23-01-18 11:53
Path: /Expertise/Published Expertise/2010-2017